The Speculist: The Promise of DNA Folding

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The Promise of DNA Folding

This could be the engine of the next economic boom:

UPDATE:Paul Rothemund has pioneered the field of DNA origami. He uses special CAD software to come up with a design:

computer smiley.jpg

He then orders long DNA strands with short "staple" DNA strands. He mixes it together and they self-assemble:

smileys.jpg

The result - 50 Billion smileys floating around in a single drop of water. In other experiments he's put circuit components on the staples and the DNA self-assembles a switch.

In order to scale this up, DNA oragami produces tiles that then bind together in predictable ways. These tiles can also count themselves. This will be handy so that the process will know when to stop. If you ask it to grow a cell phone, it has to know when to stop.

This is beyond fab-labs. This is the enabling technology for nano-factories.

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Why do I spend 50 hours a week on such unimportant nonsense when things like this are being done?

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