The Speculist: Built-in Pacemakers

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Built-in Pacemakers

What a concept:

Patients with complete heart block, or disrupted electrical conduction in their hearts, are at risk for life-threatening rhythm disturbances and heart failure. The condition is currently treated by implanting a pacemaker in the patient's chest or abdomen, but these devices often fail over time, particularly in infants and small children who must undergo many re-operations. Researchers at Children's Hospital Boston have now taken preliminary steps toward using a patient's own cells instead of a pacemaker, marking the first time tissue-engineering methods have been used to create electrically conductive tissue for the heart. Results appear in the July issue of the American Journal of Pathology (published online on June 19).

The current thinking is that this tissue won't replace pacemakers -- at least not initially -- rather it will serve as a backup to the little extremely-useful-if-somewhat-failure-prone gizmos.

Hat-tip: Dave Gobel.

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